Multi-omics analysis of glioblastoma and glioblastoma cell line: molecular insights into the functional role of gpr56 and tg2 in mesenchymal transition

HIGHLIGHTS

  • who: Raksha A. Ganesh from the University of Chicago, United States have published the article: Multi-Omics Analysis of Glioblastoma and Glioblastoma Cell Line: Molecular Insights Into the Functional Role of GPR56 and TG2 in Mesenchymal Transition, in the Journal: (JOURNAL)
  • what: The analysis showed increased secretion of tumor invasion markers, proinflammatory cytokines, pro-angiogenic factors in the CM of GPR56 knockdown cells .
  • how: The study suggests a role of GPR56 and TG2 interaction in PN to MES transition in GBM and provides insights on the putative molecular events involved rendering this interaction . . .

     

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