Treatment of allergic eosinophilic asthma through engineered il-5-anchored chimeric antigen receptor t cells

HIGHLIGHTS

• who: Sisi Chen from the Wild-type BALB/c mice were provided by the Animal Center of Slaccas (Shanghai, China)NCG (NOD/ ShiLtJGpt-Prkdcem Cd Il2rgem Cd22/Gpt) mice were provided by GemPharmatech Co [, ]. Ltd (Nanjing, China). All mouse experiments were performed under the stipulations approved by the Ethics Committee for Animal Studies of Zhejiang University (ZJU20210182). U OS cells, Plat-E cells, and HEK T cells were cultured in Dulbecco`s modified Eagle`s medium (DMEM) (HyClone) supplemented with, % FBS (Gibco) and , IU, mL penicillin and streptomycin (, mg/mL, Gibco). Jurkat cells were cultured in , medium . . .
  

   

  

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