Simultaneous onset of pediatric systemic lupus erythematosus in twin brothers: case report

HIGHLIGHTS

  • who: Mikhail M. Kostik from the Tehran University of Medical Sciences, Iran have published the Article: Simultaneous Onset of Pediatric Systemic Lupus Erythematosus in Twin Brothers: Case Report, in the Journal: (JOURNAL)
  • what: SLE in male twins is a rare and unique phenomenon.
  • how: In the recent paper the whole-exome sequencing (WES) was performed in 52/281 pediatric SLE cases who fulfilled one of the following criteria early onset of the disease ( and amplt5 years) family history of autoimmune disease and complicated conditions and causative mutations in 5 genes (SLC7A7 NRAS TNFAIP3 . . .

     

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