Clonal hematopoiesis at the crossroads of inflammatory bowel diseases and hematological malignancies: a biological link?

HIGHLIGHTS

  • who: Cosimo Cumbo from the Thomas Jefferson University, United States have published the research work: Clonal Hematopoiesis at the Crossroads of Inflammatory Bowel Diseases and Hematological Malignancies: A Biological Link?, in the Journal: (JOURNAL)

SUMMARY

    The term inflammatory bowel diseases (IBDs) define a group of chronic conditions of the gastrointestinal tract. In fact, it has been shown to alter T_cells` homeostasis and be associated with enhanced T_cell activity in recipients of allografts harboring a DNMT3A mutation. Studies are warranted to characterize the biological relationship between IBDs, CH, and HMs. the DNMT3A gene mutation . . .

     

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