Siderophore-linked ruthenium catalysts for targeted allyl ester prodrug activation within bacterial cells

HIGHLIGHTS

• who: Southwell and collaborators from the (UNIVERSITY) have published the research work: Siderophore-linked Ruthenium Catalysts for Targeted Allyl Ester Prodrug Activation within Bacterial Cells, in the Journal: (JOURNAL)
• what: The use of smallmolecule catalysts for prodrug activation within cells has shown promise in recent years and here the authors investigate siderophore-linked ruthenium catalysts for the activation of antibacterial prodrugs within cells.
• how: The experiments were carried out in aqueous MOPS buffer at physiological pH supplemented with 5 mM GSH and 10 % DMSO. Interestingly this result is in line with the fact . . .
  

   

  

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