Gain-of-function defects in toll-like receptor 8 shed light on the interface between immune system and bone marrow failure disorders

HIGHLIGHTS

• who: Jack Bleesing from the Medical University of Graz, Austria have published the Article: Gain-of-function defects in toll-like receptor 8 shed light on the interface between immune system and bone marrow failure disorders, in the Journal: (JOURNAL)
• how: The authors declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

SUMMARY

Several genes, such as IKZF1 and WAS, cause disease through different genetic mechanisms (e_g, loss-of-function mutations in WAS cause Wiskott . . .

 



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