HIGHLIGHTS
- who: Ruven Wilkens from the (UNIVERSITY) have published the research work: Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death, in the Journal: (JOURNAL) of 11/02/2022
- what: By performing bulk and single-cell transcriptomics as well as immunoblotting protein analysis the authors show that neuronal maturation is accompanied by a multitude of adaptations that render mature neurons more resistant to a variety of cellular stressors. The authors provide the first comprehensive network description of cellular adaptations in human neurons to guarantee neuronal resilience. The study design . . .
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