High dose pharmaceutical grade biotin (md1003) accelerates differentiation of murine and grafted human oligodendrocyte progenitor cells in vivo

HIGHLIGHTS

  • who: Marion J. F. Levy et al. from the INSERM, , Paris, France have published the research work: High Dose Pharmaceutical Grade Biotin (MD1003) Accelerates Differentiation of Murine and Grafted Human Oligodendrocyte Progenitor Cells In Vivo, in the Journal: (JOURNAL) of 20/04/2005
  • what: The authors show that MD1003 increases the number and the potential of endogenous murine oligodendroglia over time.
  • how: Initial clinical data showed that daily doses of MD1003 up to 300 mg over 12 months can improve objective measures of MS-related disability . To address the potential benefit of biotin . . .

     

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