Citronellal attenuates oxidative stress-induced mitochondrial damage through trpm2/nhe1 pathway and effectively inhibits endothelial dysfunction in type 2 diabetes mellitus

HIGHLIGHTS

  • who: Ya-Ling Yin and collaborators from the Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China have published the research: Citronellal Attenuates Oxidative Stress-Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus, in the Journal: Antioxidants 2022, 2241 of /2022/
  • what: The aim of this study was to investigate whether CT ameliorated T2DM-induced ED by inhibiting the TRPM2/NHE1 signal Transient receptor potential channel M2 (TRPM2) is a Ca2+ -permeable cation channel activated by oxidative stress which damages . . .

     

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