Impact of histone modifier-induced protection against autoimmune encephalomyelitis on multiple sclerosis treatment

HIGHLIGHTS

  • who: Sundararajan Jayaraman from the University of Regensburg, Germany have published the paper: Impact of histone modifier-induced protection against autoimmune encephalomyelitis on multiple sclerosis treatment, in the Journal: (JOURNAL)

SUMMARY

    The pivotal role of T helper cells in MS Cerebrospinal fluid (CSF)-infiltrating CD4+ T_cells of patients with MS proliferated and secreted interferon- γ (IFNγ), a characteristic of the Th1 subset, but not IL-17 when challenged with the myelin oligodendrocyte glycoprotein 35- 55 (MOG35-55 ) peptide in_vitro, a proposed candidate CNS determinant in MS. To Th17 cells, follicular helper T_cells that promote . . .

     

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