Impaired mitochondrial accumulation and lewy pathology in neuron-specific fbxo7-deficient mice

HIGHLIGHTS

  • who: Sachiko Noda from the of Medicine, Tokyo, u20118421, Japan Department of Neurology, Juntendo University Graduate School have published the Article: Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice, in the Journal: (JOURNAL)
  • how: To identify the relationship between the model mice and PD the authors conducted immunohistological and blot analysis in the brain.
  • future: Research is needed but the results suggest that loss of FBXO7 may affect p62 and synuclein proteolysis and impaired mitochondria elimination.

SUMMARY

    Lanes 1-3: whole-brain tissues of 3 . . .

     

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