Gemcitabine-loaded albumin nanoparticle exerts an antitumor effect on gemcitabine-resistant pancreatic cancer cells induced by mdr1 and mrp1 overexpression in vitro

HIGHLIGHTS

• who: Lei Kong and collaborators from the Medical University, China have published the article: Gemcitabine-Loaded Albumin Nanoparticle Exerts An Antitumor Effect on Gemcitabine-Resistant Pancreatic Cancer Cells Induced by MDR1 and MRP1 Overexpression in Vitro, in the Journal: (JOURNAL)
• what: The authors aimed to investigate the antitumor effect of human serum nanoparticle (GEM-HSA-NP) on GEMresistant pancreatic cancer cells induced by the high expression of ABC transporters namely multidrug resistance protein 1/P-gp/ABCB1 (MDR1) and multidrug resistanceassociated protein 1/ ABCC1 (MRP1). The authors selected BxPC3 and PANC1 cell lines for the . . .
  

   

  

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