HIGHLIGHTS
- who: Gu00fcnter Hu00f6glinger from the German Center for Neurodegenerative Diseases (DZNE) Rostock/Greifswald, Gehlsheimer Str20, Rostock, Germany have published the research: GBA-associated PD: chances and obstacles for targeted treatment strategies, in the Journal: (JOURNAL)
SUMMARY
Variants in the glucocerebrosidase (GBA) gene (PDGBA). Subsequently, a large multi-centre study across four continents analysed 5691 PD patients of different ethnic origin compared to 4898 controls and confirmed that with an overall odds ratio (OR) of 5.43, heterozygous variants in the GBA gene represent the most important genetic risk factor for PD (Sidransky et_al . . .
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