HIGHLIGHTS
- who: Maxwell A. Sherman from the Massachusetts Institute, Boston, MA, USAUniversity of have published the paper: Genome-wide mapping of somatic mutation rates uncovers drivers of cancer, in the Journal: (JOURNAL) of 20/08/2021
- how: To enable rapid evaluation of mutational excess anywhere in the genome the authors designed Dig to model somatic mutation rates genome-wide for a given type of cancer. The authors then benchmarked the accuracy of the somatic mutation rate models using the metric of proportion of variance explained which the authors calculated as the square of the correlation coefficient . . .
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