Role of ll-37 in thrombotic complications in patients with covid-19

HIGHLIGHTS

  • who: Zilei Duan from the Laboratory (Guangzhou), Guangzhou, China Southwest Hospital, Third Military have published the research: Role of LL-37 in thrombotic complications in patients with COVID-19, in the Journal: (JOURNAL)
  • what: The authors analyzed coagulation function and found a decrease in thrombin time but an increase in fibrinogen level prothrombin time and activated partial thromboplastin time in COVID-19 patients.
  • how: Showed that increased LL-37 was correlated with COVID-19-related coagulation dysfunction. The authors showed that LL-37 induced hypercoagulability through enhancement of coagulation factor activity.
 

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