Purinoreceptors and ectonucleotidases control atp-induced calcium waveforms and calcium-dependent responses in microglia: roles of p2 receptors and cd39 in atp-stimulated microglia

HIGHLIGHTS

• who: . et al. from the The University of Melbourne, Australia have published the paper: Purinoreceptors and ectonucleotidases control ATP-induced calcium waveforms and calcium-dependent responses in microglia: Roles of P2 receptors and CD39 in ATP-stimulated microglia, in the Journal: (JOURNAL)
• what: With this model, the authors specifically examined how P2X- and P2Y-class purinoreceptors encode ATP-triggered Ca2+ waveforms in microglia, how these waveforms are modulated by the ectonucleotidase CD39, and how these waveforms influence migration and cytokine responses. In Figure 3B, the authors demonstrate that the activation of P2Y by ATP and . . .
  

   

  

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