Apobec mutagenesis is a common process in normal human small intestine

HIGHLIGHTS

• who: Yichen Wang from the (UNIVERSITY) have published the Article: APOBEC mutagenesis is a common process in normal human small intestine, in the Journal: (JOURNAL) of 16/Dec/2022
• what: This study shows that the total somatic mutation rates of small intestine stem_cells are similar to those of the colorectum, confirming previous results12,25.

SUMMARY

There is an incomplete understanding of its stimulus, when it occurs in the progression from normal to cancer cell and the APOBEC enzymes responsible. The authors whole-genome sequenced 342 microdissected normal epithelial crypts from the . . .

 



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