HIGHLIGHTS
- who: Hao Zhang and collaborators from the Jiaotong University, China have published the paper: RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis, in the Journal: (JOURNAL)
- what: Taken together, the work demonstrates the significant role of CD44 in the progression and treatment of gliomas.
- how: Higher CD44 expression is found in glioma patients with poor survival Consequently the authors evaluated prognostic value concerning the different CD44 levels in gliomas through Kaplan-Meier analysis. In contrast the overexpression of RUNX1 alleviated the decreased clone formation capacity . . .
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