HIGHLIGHTS
- who: Christin Pohl from the , Denmark, Technical University of have published the research: pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The study of anti-microbial polymers has mainly focused on their synthetic design to overcome challenges in immunogenicity, off-target effects and serum instability and ensure their controlled release43-45. The authors show that the introduced mutations improved anti-microbial potency against Staphylococci compared to wildtype and retained activity against Streptococci clinical isolates. The authors characterize the . . .
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