HIGHLIGHTS
- who: December and colleagues from the University of Texas at Tyler, United States have published the paper: Cerebrospinal uid concentrations of fl uoroquinolones and carbapenems in tuberculosis meningitis, in the Journal: (JOURNAL)
- what: All fluoroquinolones in the study had median serum Cmax values within normal ranges (8-12 mg/L for levofloxacin and providing data that continued moderate-high CSF concentrations can be obtained during treatment. While current clinical trial data have not shown an ability of fluoroquinolones to improve outcomes among patients treated for drug-susceptible TBM, the study provides key pharmacokinetic data for . . .
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