Histone deacetylase 3 facilitates tnfα-mediated nf-κb activation through suppressing ctsb induced rip1 degradation and is required for host defense against bacterial infection

HIGHLIGHTS

• who: Liping Yang from the Department of Infectious Diseases, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China have published the article: Histone deacetylase 3 facilitates TNFu03b1-mediated NF-u03baB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection, in the Journal: (JOURNAL)
• what: The studies showed that Vector and Hdac3-/- RAW264.7 cells were stimulated with TNFu03b1, both the total and phosphorylated RIP1 levels were significantly lower in Hdac3-/- as compared to Vector RAW264.7 cells (Fig 5A, B).
• how: These data indicated . . .
  

   

  

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