Liver rbfox2 regulates cholesterol homeostasis via scarb1 alternative splicing in mice

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• who: Helen A. B. Paterson from the (UNIVERSITY) have published the Article: Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice, in the Journal: Nutrition-promoted changes in the liver splicing machinery To investigate liver metabolic plasticity during health and disease, we conducted unbiased analyses of the liver transcriptome (RNA-sequencing, RNA-seq) and proteome (tandem mass tag-mass spectrometry, TMT-MS) of mice fed either control (CD) or high-fat diets (HFD), under both fed and starved conditions (Fig. 1a). Proteomic analysis identified 5,999 proteins in all experimental conditions (Supplementary Table 1). Principal . . .
  

   

  

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