Evaluation of taxonomic classification and profiling methods for long-read shotgun metagenomic sequencing datasets

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SUMMARY

    Prior long-read benchmarking studies applied short-read methods to long reads or compared the potential of long reads to short reads, yet only one study has included a comparison of long-read methods. Given the dramatic decreases in long read error rates and the proliferation of long read classification methods, there is a pressing need to assess the performance of taxonomic profiling using long reads. The authors distinguish long-read methods from short-read methods as those which utilize the long-range information contained across a long read (often using multiple genes for . . .

     

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