Graph-based autoencoder integrates spatial transcriptomics with chromatin images and identifies joint biomarkers for alzheimer⠒s disease

HIGHLIGHTS

• who: Xinyi Zhang from the (UNIVERSITY) have published the Article: Graph-based autoencoder integrates spatial transcriptomics with chromatin images and identifies joint biomarkers for Alzheimeru2812s disease, in the Journal: (JOURNAL) of 23/Nov/2022
• what: Collectively, the authors demonstrate the importance of characterizing disease progression by integrating multiple data modalities and its potential for the discovery of disease biomarkers. Although no data on amyloid plaque distribution was used in training the model , the three cortex clusters identified by the model show different distributions of amyloid plaques (Fig 2g, h). Next, the authors examine which chromatin . . .
  

   

  

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