Integrin 2 and 1 cross-communication with mtor/akt and the cdk-cyclin axis in hepatocellular carcinoma cells

HIGHLIGHTS

  • who: Mazen A. Juratli and collaborators from the Department of General and Visceral Surgery, Goethe-University, Frankfurt am Main, Germany have published the article: Integrin 2 and 1 Cross-Communication with mTOR/AKT and the CDK-Cyclin Axis in Hepatocellular Carcinoma Cells, in the Journal: Cancers 2022, 2430 of /2022/
  • what: This study was designed to explore the links between integrins and the AKT-mTOR pathway and the CDK-Cyclin axis. This investigation provides evidence for the first time that the integrin u03b12/u03b21-collagen interaction also activates pathways relevant for mitotic HCC progression. This . . .

     

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