HIGHLIGHTS
- who: David Giacalone and colleagues from the Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston have published the Article: PrrA modulates Mycobacterium tuberculosis response to multiple environmental cues and is critically regulated by serine/threonine protein kinases, in the Journal: (JOURNAL)
- what: The authors exploit a pH/Cl--responsive luminescent reporter Mtb strain in combination with a tetracycline-inducible TF overexpression plasmid library in a phenotypic screen, identifying PrrA, an essential TF that is part of the PrrAB TCS, as a global modulator of Mtb response to not just pH and . . .
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