HIGHLIGHTS
- who: August and colleagues from the Bam University of Medical Sciences and Health Services, Iran have published the research work: Comprehensive review of -carboline alkaloids: Natural products, updated synthesis, and biological activities, in the Journal: (JOURNAL)
- how: The results showed that all compounds belonging to the 5H series (e_g 51) i.e. bearing a methyl on the pyridine nitrogen atom displayed marked cytotoxicity against KB cells with IC50 values in the range of 2 u00d7 10-3 to 9 u00d7 10-3 u03bcM. The results indicated that the existence and position of the guanyl moiety . . .
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