Swi/snf chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress

HIGHLIGHTS

  • who: Abdallah Zayed from the CNRS Research University, Paris, France have published the research work: SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that stress exposure induces a stable reorganization of GR and BRG1 nuclear distribution within striatal medium spiny neurons (MSNs). The authors showed that SWI/SNF complexes are essential for some behavioral adaptation to stress exposure through transcriptional responses, a phenomenon essential to adjust behavior to environmental challenges.
  • how: Interestingly the fact . . .

     

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