HIGHLIGHTS
SUMMARY
Individual participant data (IPD) meta-analyses, which utilise more granular data, are even more powerful than meta-analysis of studies where only overall results are considered. Combining data in meta-analyses allows for broader overarching questions - such as determining if there are non-specific disease signatures in the respiratory microbiota - to be investigated in a manner that is largely unfeasible within a single study. Standardised frameworks specifying minimum reporting criteria for microbiome studies have emerged (e_g MIxS, STORMS and STROBE metagenomics ); however, such frameworks are not yet widely or consistently applied, and their suitability . . .
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