Extracellular matrix changes in subcellular brain fractions and cerebrospinal fluid of alzheimer’s disease patients

HIGHLIGHTS

  • who: Lukas Hu00f6hn et al. from the Leibniz Institute for Neurobiology (LIN), Magdeburg, Germany Department of Neurology, Otto-von-Guericke University, Magdeburg, Germany have published the research work: Extracellular Matrix Changes in Subcellular Brain Fractions and Cerebrospinal Fluid of Alzheimeru2019s Disease Patients, in the Journal: (JOURNAL) of 11/Oct/2022
  • what: To circumvent these problems, in the study the authors used antibodies to detect several key components of the hyaluronan-binding neural ECM, namely the lecticans brevican, neurocan, aggrecan and the link protein HAPLN1/Crtl1, in subcellular fractions from three different post-mortem brain areas . . .

     

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