HIGHLIGHTS
- who: Shimin Chen from the Children`s Hospital of Wenzhou Medical, China have published the research work: FBXW7 attenuates tumor drug resistance and enhances the efficacy of immunotherapy, in the Journal: (JOURNAL)
- what: The third mechanism is histologic transformation, such as squamous transformation, which is one of the primary reasons for resistance to First-line Osimertinib in EGFR-mutant lung cancer .
SUMMARY
Both in_vitro and in_vivo studies reveal that the knockdown of FBXW7 enhances the invasion and migration in GC. What`s more, some experiments using FBXW7 knockout mouse models constructed . . .
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