HIGHLIGHTS
- who: Mohammad A. Ghane from the University of Texas Southwestern Medical Center, United States have published the article: Arc ubiquitination regulates endoplasmic reticulum-mediated Ca 2+ release and CaMKII signaling, in the Journal: (JOURNAL)
- what: It is possible that this model has increased DHPG-induced ER-Ca2+ release similar to the ArcKR mice.
- how: The authors used this conservative mutation and co-transfected HEK293 cells with N-terminal myctagged Arc (myc-ArcWT) or ArcKR (myc-ArcKR) and N-terminal GFP-tagged Arc (GFP-ArcWT) and GFP-ArcKR and performed a co-immunoprecipitation assay . . .
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