HIGHLIGHTS
- who: Gaia Codolo and collaborators from the University of Colorado, United States have published the Article: HP-NAP of Helicobacter pylori: The Power of the Immunomodulation, in the Journal: (JOURNAL)
SUMMARY
CAR T_cells engineering to produce HP-NAP turned out to be a very promising approach for treating solid tumors that are difficult to completely eradicate with conventional CAR T_cells, due to heterogeneity in antigen expression. In mouse models of cancer, injection of CAR(NAP) T_cells slowed tumor growth and increased survival rates compared to standard mice CAR T_cells, regardless of target antigen . . .
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