HIGHLIGHTS
- who: Xin Gao and collaborators from the School Pharmacy, Fudan University, Shanghai, China have published the article: Intraocular siRNA Delivery Mediated by Penetratin Derivative to Silence Orthotopic Retinoblastoma Gene, in the Journal: Pharmaceutics 2023, 15, x FOR PEER REVIEW of /2023/
- what: The authors developed an ocular gene delivery system consisting of a cationic polymer (PAMAM) and an optimized cell-penetrating peptide (89WP). The authors successfully constructed a noninvasive intraocular gene delivery system, in which the 3rd generation PAMAM dendrimer compressed siRNA to form the primary polyplex siRNA/PA and then the penetratin derivative 89WP . . .
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