Bioinformatics analysis reveals the potential role of matrix metalloproteinases in immunity and urolithiasis

HIGHLIGHTS

SUMMARY

    MMPs were also found to be involved in immunity and inflammation, serving as modulators of immune_response and inflammatory processes, which can influence and shaped the phenotype of immune cells. The authors performed weighted gene coexpression network analysis (WGCNA) and three machine_learning algorithms to screen the hub DEMMPs. The authors took the intersection between DEMMPs and genes in urolithiasis-related modules to obtain the hub DEMMPs Machine learning Three machine_learning algorithms were used to screen the hub DEMMPs. For GO terms, activation of immune_response, acute inflammatory response, acute phase response, and adaptive immune_response were enriched . . .

     

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