Hepatotoxicity of small molecule protein kinase inhibitors for cancer

HIGHLIGHTS

  • who: Mauro Viganu00f2 and collaborators from the Gastroenterology Hepatology and Transplantation Unit, ASST Papa Giovanni XXIII, Bergamo, Italy Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Palermo, Italy have published the research: Hepatotoxicity of Small Molecule Protein Kinase Inhibitors for Cancer, in the Journal: Cancers 2023, 1766 of /2023/
  • what: Future Directions Despite the progress of PKIs for cancer treatment, the safety issues are often the main reason for their reduced effectiveness in the real practice since toxicity (and particularly hepatotoxicity) may cause their temporary or definitive discontinuation. All the research efforts must . . .

     

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