HIGHLIGHTS
- who: . et al. from the University California, Davis, United States have published the paper: CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway, in the Journal: (JOURNAL)
- how: Biochemical measurements in the serum of double knockout mice generated during the course of the study revealed increased transaminase levels which is in agreement with the It should be noted that mice lacking both Cth and Mpst have been previously generated independently using a CRISPR/Cas9 approach (Akahoshi et_al 2020) however the cardiovascular phenotype of these mice . . .
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