Independent validation of a dysphagia dose response model for the selection of head and neck cancer patients to proton therapy

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SUMMARY

    This study examined dosimetric photon and proton based NTCP parameters differences by internally validating the NTCP model of Lyman-Kutcher-Burman (LKB) using prospective treatment and morbidity data of PT treated prostate cancer patients. The authors highlighted the importance of NTCP models upĀ­ date and external validation due to clinical practice patterns changes as they concluded that dosimetric parameters such as the mean dose to 50 % of the target volume (D50) was different from the typical photonbased LKB NTCP model. Despite the initial goal to externally validate the NTCP dysphagia model using an independent . . .

     

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