Regulation of tia-1 condensates: zn and rgg motifs promote nucleic acid driven llps and inhibit irreversible aggregation

HIGHLIGHTS

  • who: RGG motif et al. from the Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia, Institute for Chemical Research, University of Seville-CSIC, Seville, Spain have published the research work: Regulation of TIA-1 Condensates: Zn and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation, in the Journal: (JOURNAL)
  • what: The authors investigate the effect of stress granule co-factors on LLPS and fibril formation of TIA-1 in_vitro. The authors report the impacts of Zn2+ and FUS-RBD on TIA-1 in the . . .

     

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