Omega-class glutathione transferases protect dna from oxidative stress in pathogenic helminth reproductive cells

HIGHLIGHTS

• who: Jeong-Geun Kim and collaborators from the Department of Molecular Parasitology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea have published the paper: Omega-Class Glutathione Transferases Protect DNA from Oxidative Stress in Pathogenic Helminth Reproductive Cells, in the Journal: Antioxidants 2023, 560 of 24/08/2022
• what: The authors show that transferases (GSTOs) are critical for maintaining viability by protecting the reproductive cell DNA of the carcinogenic liver fluke Clonorchis sinensis. This study shows that CsGSTO1 and CsGSTO2 catalyze deglutathionylation under physiologic and low oxidative stress conditions while they . . .
  

   

  

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