Transcriptional activation of ecdysone-responsive genes requires h3k27 acetylation at enhancers

HIGHLIGHTS

  • who: Dong Cheng and collaborators from the State Key Laboratory of Silkworm Genome Biology, Biological Science Research Center, Southwest University, Chongqing, China have published the article: Transcriptional Activation of Ecdysone-Responsive Genes Requires H3K27 Acetylation at Enhancers, in the Journal: (JOURNAL) of 20/08/2021
  • what: The authors aimed to clarify the role of ecdysone in epigenetic regulation and, particularly, in histone acetylation.
  • how: The results showed that the EcR plays a central role in H3K27 acetylation and chromatin accessibility by recruiting the histone acetyltransferase CBP at enhancers. The results showed that the . . .

     

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