Peptides from the sea anemone metridium senile with modified inhibitor cystine knot (ick) fold inhibit nicotinic acetylcholine receptors

HIGHLIGHTS

• who: Igor E. Kasheverov and colleagues from the Miklukho-Maklaya, Moscow, Russia Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya str8, bld, have published the research: Peptides from the Sea Anemone Metridium senile with Modified Inhibitor Cystine Knot (ICK) Fold Inhibit Nicotinic Acetylcholine Receptors, in the Journal: Toxins 2023, 28 of /2023/
• what: Novel biologically active peptides Ms11a-1-Ms11a-4 inhibiting nAChRs were isolated from the venom of sea anemone M. senile.
• how: The binding results were analyzed using the OriginPro 2015 program (OriginLab Corporation Northampton MA USA) fitting . . .
  

   

  

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