Rational design of gdp‑d‑mannose mannosyl hydrolase for microbial l‑fucose production

HIGHLIGHTS

• who: Cong Fu from the (UNIVERSITY) have published the paper: Rational design of GDPu2011du2011mannose mannosyl hydrolase for microbial lu2011fucose production, in the Journal: (JOURNAL)
• what: We engineered B. subtilis for the production of a valuable monosaccharide, l-fucose, from an ecou2011 nomic carbon source combined with the rational design of GDPu2011du2011mannose mannosyl hydrolase and de novo construction of the related pathway.

SUMMARY

L‑Fucose (6‑deoxy‑l‑galactose) is an indispensable component of mammalian glycans and glycolipids, and the O‑fucosylation of glycans and glycolipids is bio‑ logically important due to . . .

 



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