Aged g protein-coupled receptor kinase 3 (grk3)-deficient mice exhibit enhanced osteoclastogenesis and develop bone lesions analogous to human paget’s disease of bone

HIGHLIGHTS

• who: Emily M. Rabjohns and colleagues from the Division of Rheumatology and Immunology, Duke University Department of Medicine, Durham, NC, USA have published the research work: Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Pagetu2019s Disease of Bone, in the Journal: Cells 2023, 981 of /2023/
• what: The authors report that expression increases during osteoclast differentiation in both human and mouse primary cells and established cell lines. The authors show that a deficiency in expression enhances in vitro and proliferation of hematopoietic osteoclast . . .
  

   

  

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