HIGHLIGHTS
- who: input2 from the (UNIVERSITY) have published the paper: Influence of Tyrosyl-DNA Phosphodiesterase 1 Inhibitor on the Proapoptotic and Genotoxic Effects of Anticancer Agent Topotecan, in the Journal: (JOURNAL)
- what: In this work it was shown that the combined use of topotecan and inhibitor the hydrazonothiazole derivative of usnic acid OL9-119 leads to an increase in the DNA-damaging effect of topotecan which is used in the clinic for the treatment of cancer.
SUMMARY
The covalent complex Top1-DNA is normally short-lived, but can a Institute CHEPANOVA et_al . . .
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