Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock

HIGHLIGHTS

  • who: N. Patel from the DepartmentUniversity of have published the research: Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock, in the Journal: Scientific Reports Scientific Reports
  • what: This study sought to mitigate IRI in a pig model of hemorrhagic shock and profound ischemia by using a peptide developed to protect mitochondrial function. The study showed that largevolume isotonic crystalloid resuscitation provided no overall survival benefit.
  • how: An overview of the study is provided in Fig 1. | Vol.(1234567890) 134496 | established percutaneously with the Seldinger technique under ultrasound guidance.
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