Microglia impairs proliferation and induces senescence in-vitro in ngf releasing cells used in encapsulated cell biodelivery for alzheimer’s disease therapy

HIGHLIGHTS

  • who: Sumonto Mitra and colleagues from the Division of Clinical Geriatrics, Center for Alzheimer Research, Department of NVS, Karolinska Institutet, Inc, Providence, RI, USA and, Karolinska University Hospital, , have published the research work: Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimeru2019s Disease Therapy, in the Journal: (JOURNAL) of 11/07/2022
  • what: The authors report here that cells can impair hmNGF release from ECB-NGF devices in-vitro which can be reversed by transferring the devices to fresh culture medium. The authors aimed to . . .

     

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