HIGHLIGHTS
SUMMARY
Instead of being a standalone biosignature, O2 as a biosignature will be most powerful when detected simultaneously with a reducing gas as a "disequilibrium biosignature pair" (e_g, Lovelock 1965; Lederberg 1965; Lippincott et_al 1967), and when evidence of abiotic O2 production scenarios can be ruled out (see Meadows 2017; Meadows et_al 2018b for a review). In scenarios where O2 is not directly detectable, it has been suggested that its photochemical product ozone (O3 ) could be used as a proxy for O2 (e_g, Leger et_al 1993; Des Marais et_al 2002; Segura et_al 2003; Léger . . .
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