Ppars and the kynurenine pathway in melanoma—potential biological interactions

HIGHLIGHTS

  • who: Katarzyna Walczak and colleagues from the Laboratory for Immunology of Skin Diseases, Chair and Department of, Venerology and, Medical University of Lublin, Radziwillowska, Lublin, Poland have published the research work: PPARs and the Kynurenine Pathway in Melanomau2014Potential Biological Interactions, in the Journal: (JOURNAL)
  • what: In this review the authors focused not only on the activity of PPAR isoforms in initiation progression and metastasis but also on interactions between the PPAR signaling and the kynurenine pathways. The study aims to evaluate whether adding metformin or rosiglitazone, a PPARy agonist, will act synergistically with anti-PD . . .

     

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