The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in ibd

HIGHLIGHTS

  • who: Jessica Astorga from the University College Cork, Ireland Georgia State University, United States have published the research: The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD, in the Journal: (JOURNAL)
  • what: IBD is characterized by a loss of intestinal barrier function and inflammation.
  • future: The role of altered cholesterol trafficking and accumulation in IBD inflammation is an emerging area that offers new perspectives to understanding the pathogenic mechanisms of IBD. Although no FAD+ data is available in IBD lower levels are expected due to decreased complex II . . .

     

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